two-tailed chi-square with yate’s 281 correction online Search Results


chi-squared analysis  (CH Instruments)
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Chi Squared Analysis, supplied by CH Instruments, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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chi-square  (CH Instruments)
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CH Instruments chi-square
Chi Square, supplied by CH Instruments, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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two-tailed chi-square test with yates correction  (CH Instruments)
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CH Instruments two-tailed chi-square test with yates correction
Two Tailed Chi Square Test With Yates Correction, supplied by CH Instruments, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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chi-square two-tailed test  (CH Instruments)
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Chi Square Two Tailed Test, supplied by CH Instruments, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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statistical software v.11.1.1.0  (MedCalc Software Ltd)
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Statistical Software V.11.1.1.0, supplied by MedCalc Software Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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square analysis with yates correction  (CH Instruments)
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Square Analysis With Yates Correction, supplied by CH Instruments, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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chi-square test  (CH Instruments)
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CH Instruments chi-square test
Chi Square Test, supplied by CH Instruments, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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pearson chi-square test  (CH Instruments)
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Pearson Chi Square Test, supplied by CH Instruments, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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two-tailed chi-square test  (CH Instruments)
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Two Tailed Chi Square Test, supplied by CH Instruments, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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statistical software medcalc v.11.1.1.0  (MedCalc Software Ltd)
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v h replacement products  (CH Instruments)
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CH Instruments v h replacement products
Frequencies of <t> V H replacement </t> footprint motifs in the N1 and N2 regions of human IgH genes .
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yates’ chi-square  (CH Instruments)
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CH Instruments yates’ chi-square
Frequencies of <t> V H replacement </t> footprint motifs in the N1 and N2 regions of human IgH genes .
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Image Search Results


Frequencies of V H replacement footprint motifs in the N1 and N2 regions of human IgH genes .

Journal: Frontiers in Immunology

Article Title: Accumulation of V H Replacement Products in IgH Genes Derived from Autoimmune Diseases and Anti-Viral Responses in Human

doi: 10.3389/fimmu.2014.00345

Figure Lengend Snippet: Frequencies of V H replacement footprint motifs in the N1 and N2 regions of human IgH genes .

Article Snippet: The frequency of V H replacement products in non-functional IgH genes (18%) is extremely statistically significantly higher than that in the overall functional IgH genes ( p < 0.0001, two-tailed Chi square test with Yates’ correction).

Techniques:

Identification of potential V H replacement products in human IgH sequences .

Journal: Frontiers in Immunology

Article Title: Accumulation of V H Replacement Products in IgH Genes Derived from Autoimmune Diseases and Anti-Viral Responses in Human

doi: 10.3389/fimmu.2014.00345

Figure Lengend Snippet: Identification of potential V H replacement products in human IgH sequences .

Article Snippet: The frequency of V H replacement products in non-functional IgH genes (18%) is extremely statistically significantly higher than that in the overall functional IgH genes ( p < 0.0001, two-tailed Chi square test with Yates’ correction).

Techniques:

Distribution of V H replacement products in IgH genes using different V H genes . The frequencies of V H replacement products in functional IgH genes using each V H germline genes are compared with that in IgH genes using the V H6-1 gene. ** p < 0.0001, * p < 0.05. The result for IgH genes using the V H6-1 gene is highlighted in the box and the frequency of V H replacement products in all the IgH genes is indicated by the dashed line.

Journal: Frontiers in Immunology

Article Title: Accumulation of V H Replacement Products in IgH Genes Derived from Autoimmune Diseases and Anti-Viral Responses in Human

doi: 10.3389/fimmu.2014.00345

Figure Lengend Snippet: Distribution of V H replacement products in IgH genes using different V H genes . The frequencies of V H replacement products in functional IgH genes using each V H germline genes are compared with that in IgH genes using the V H6-1 gene. ** p < 0.0001, * p < 0.05. The result for IgH genes using the V H6-1 gene is highlighted in the box and the frequency of V H replacement products in all the IgH genes is indicated by the dashed line.

Article Snippet: The frequency of V H replacement products in non-functional IgH genes (18%) is extremely statistically significantly higher than that in the overall functional IgH genes ( p < 0.0001, two-tailed Chi square test with Yates’ correction).

Techniques: Functional Assay

V H replacement products are significantly enriched in IgH genes derived from autoimmune diseases or viral infections and in IgH genes encoding autoreactive or anti-viral Abs . Frequencies of V H replacement products in IgH gene sequences derived from different sub-categories were analyzed based on the identification of pentameric V H replacement footprints within their V–D junctions. The frequencies of V H replacement products in IgH genes derived from different autoimmune diseases and viral infections, or in IgH genes encoding auto Abs, anti-viral Abs, or anti-bacterial Abs were compared with that from healthy controls. The number of analyzed IgH gene sequences in each subcategory are indicated ( n ). The arrow head indicates the overall frequency of V H replacement products (12.1%) in the 39,438 unique human IgH sequences. Statistical significance was determined using a two-tailed Chi square test with Yate’s correction. * p < 0.05 is considered statistically significant and ** p < 0.0001 is considered extremely statistically significant.

Journal: Frontiers in Immunology

Article Title: Accumulation of V H Replacement Products in IgH Genes Derived from Autoimmune Diseases and Anti-Viral Responses in Human

doi: 10.3389/fimmu.2014.00345

Figure Lengend Snippet: V H replacement products are significantly enriched in IgH genes derived from autoimmune diseases or viral infections and in IgH genes encoding autoreactive or anti-viral Abs . Frequencies of V H replacement products in IgH gene sequences derived from different sub-categories were analyzed based on the identification of pentameric V H replacement footprints within their V–D junctions. The frequencies of V H replacement products in IgH genes derived from different autoimmune diseases and viral infections, or in IgH genes encoding auto Abs, anti-viral Abs, or anti-bacterial Abs were compared with that from healthy controls. The number of analyzed IgH gene sequences in each subcategory are indicated ( n ). The arrow head indicates the overall frequency of V H replacement products (12.1%) in the 39,438 unique human IgH sequences. Statistical significance was determined using a two-tailed Chi square test with Yate’s correction. * p < 0.05 is considered statistically significant and ** p < 0.0001 is considered extremely statistically significant.

Article Snippet: The frequency of V H replacement products in non-functional IgH genes (18%) is extremely statistically significantly higher than that in the overall functional IgH genes ( p < 0.0001, two-tailed Chi square test with Yates’ correction).

Techniques: Derivative Assay, Two Tailed Test

The average CDR3 length of identified V H replacement products is significantly longer than that of non-V H replacement products . The distribution of IgH genes with different CDR3 lengths is shown in the bar graph. The average CDR3 length of V H replacement products (black bars) was compared to that of non-V H replacement products (white bars). Statistical significance was determined by using an unpaired t -test. ** p < 0.0001 is considered extremely statistically significant.

Journal: Frontiers in Immunology

Article Title: Accumulation of V H Replacement Products in IgH Genes Derived from Autoimmune Diseases and Anti-Viral Responses in Human

doi: 10.3389/fimmu.2014.00345

Figure Lengend Snippet: The average CDR3 length of identified V H replacement products is significantly longer than that of non-V H replacement products . The distribution of IgH genes with different CDR3 lengths is shown in the bar graph. The average CDR3 length of V H replacement products (black bars) was compared to that of non-V H replacement products (white bars). Statistical significance was determined by using an unpaired t -test. ** p < 0.0001 is considered extremely statistically significant.

Article Snippet: The frequency of V H replacement products in non-functional IgH genes (18%) is extremely statistically significantly higher than that in the overall functional IgH genes ( p < 0.0001, two-tailed Chi square test with Yates’ correction).

Techniques:

V H replacement footprints preferentially contribute charged amino acids into the IgH CDR3 regions . (A) Frequencies of charged and uncharged amino acids (aa) in the N1 regions of non-V H replacement products were compared with those encoded by the V H replacement footprints. (B) The usages of different amino acids in the N1 regions of non-V H replacement products (white bars) or encoded by the V H replacement footprints (black bars) were analyzed and shown in the bar graph. The total number of amino acids analyzed for each population is indicated. Statistical significance was determined using a two-tailed Chi square test with Yate’s correction. * p < 0.05 is considered statistically significant. ** p < 0.0001 is considered extremely statistically significant.

Journal: Frontiers in Immunology

Article Title: Accumulation of V H Replacement Products in IgH Genes Derived from Autoimmune Diseases and Anti-Viral Responses in Human

doi: 10.3389/fimmu.2014.00345

Figure Lengend Snippet: V H replacement footprints preferentially contribute charged amino acids into the IgH CDR3 regions . (A) Frequencies of charged and uncharged amino acids (aa) in the N1 regions of non-V H replacement products were compared with those encoded by the V H replacement footprints. (B) The usages of different amino acids in the N1 regions of non-V H replacement products (white bars) or encoded by the V H replacement footprints (black bars) were analyzed and shown in the bar graph. The total number of amino acids analyzed for each population is indicated. Statistical significance was determined using a two-tailed Chi square test with Yate’s correction. * p < 0.05 is considered statistically significant. ** p < 0.0001 is considered extremely statistically significant.

Article Snippet: The frequency of V H replacement products in non-functional IgH genes (18%) is extremely statistically significantly higher than that in the overall functional IgH genes ( p < 0.0001, two-tailed Chi square test with Yates’ correction).

Techniques: Two Tailed Test

V H replacement footprints preferentially contribute charged amino acids into the CDR3 regions of IgH genes derived from autoimmune diseases and viral infections . (A) Frequencies of charged and uncharged amino acids encoded by the V H replacement footprints in IgH genes derived from autoimmune diseases and viral infections. n , Total number of amino acids analyzed in each subcategory. (B) Frequencies of negatively and positively charged residues encoded by the V H replacement footprints in IgH genes derived from autoimmune diseases or viral infections. Statistical significance was determined using a two-tailed Chi square test with Yate’s correction. * p < 0.05 is considered statistically significant. (C) Comparison of overall somatic mutation rates (%) within V H region of V H replacement products versus non-V H replacement products in different sub-categories.

Journal: Frontiers in Immunology

Article Title: Accumulation of V H Replacement Products in IgH Genes Derived from Autoimmune Diseases and Anti-Viral Responses in Human

doi: 10.3389/fimmu.2014.00345

Figure Lengend Snippet: V H replacement footprints preferentially contribute charged amino acids into the CDR3 regions of IgH genes derived from autoimmune diseases and viral infections . (A) Frequencies of charged and uncharged amino acids encoded by the V H replacement footprints in IgH genes derived from autoimmune diseases and viral infections. n , Total number of amino acids analyzed in each subcategory. (B) Frequencies of negatively and positively charged residues encoded by the V H replacement footprints in IgH genes derived from autoimmune diseases or viral infections. Statistical significance was determined using a two-tailed Chi square test with Yate’s correction. * p < 0.05 is considered statistically significant. (C) Comparison of overall somatic mutation rates (%) within V H region of V H replacement products versus non-V H replacement products in different sub-categories.

Article Snippet: The frequency of V H replacement products in non-functional IgH genes (18%) is extremely statistically significantly higher than that in the overall functional IgH genes ( p < 0.0001, two-tailed Chi square test with Yates’ correction).

Techniques: Derivative Assay, Two Tailed Test, Comparison, Mutagenesis